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Potentially Inappropriate Medications to Be Used with Caution in Older Adults
Latest Research
| Drug(s) | Rationale | Recommendation |
| Aspirin to prevent heart attacks and other "cardiac events" | In adults 80-years-old and older, aspirin may do more harm than good | Use aspirin with caution in adults 80 and older. |
| Dabigatran | This medication, used to prevent the formation of blood clots in patients with atrial fibrillation, increases the chance of bleeding in adults 75 years and older more than another drug, warfarin, that is used for the same purpose. There isn't enough evidence that dabigatran is effective and safe in patients with kidney problems. |
Use this drug with caution in adults 75 and in older adults with kidney problems. |
| Prasugrel | This drug can increase the chance of bleeding in older adults, but may be appropriate for some older adults at very high risk of future heart problems. | Use with caution in adults 75 years or older. |
| Antipsychotics Carbamazepine Carboplatin Cisplatin All antidepressants Vincristine |
These drugs may lower your blood sodium level to dangerous levels. Healthcare providers should monitor patients taking these medications. | Use with caution. |
| Vasodilators | These drugs may increase risks of fainting in older adults with a history of fainting. | Use with caution. |