Peripheral Artery Disease

Care & Treatment

Most cases of peripheral artery disease can be managed with lifestyle changes (such as diet and exercise) and medications. If you have diabetes, high blood pressure, or other conditions related to peripheral artery disease, your healthcare provider will work with you to closely manage and monitor these conditions.


Medications that your healthcare provider may prescribe include: 

  • Aspirin or other blood-thinning medication to help prevent blood clots from forming and to aid blood flow through narrowed arteries.
  • Cilostazol, a medication that may be used to help improve leg pain and increase walking distance. 
  • Cholesterol-lowering drugs (statins), which may be recommended in patients with peripheral artery disease because they can reduce symptoms and the need for surgery and amputations.
  • Blood pressure medications, if your blood pressure is high. 


If you still have significant symptoms and difficulty with your daily activities despite exercise and medications, or if blood flow becomes severely reduced, your doctor may recommend a surgical procedure. The specific procedure depends on the location of the blockage, your other medical conditions, and your preferences for treatment.

Endovascular Surgery

Endovascular surgeries are done inside the artery and without big incisions on the skin. Many people are familiar with angioplasty (inflating a balloon) or stenting (placing a small metal or plastic mesh tube) to open a blocked artery in the heart. These same procedures can also be used to open blocked arteries in the legs.

Bypass Surgery 

Similar to heart bypass surgery, bypass surgery can also be done in the legs. This involves taking a blood vessel from another part of your body, or using a synthetic tube, and inserting it in the area where the artery is blocked so the blood can flow around (bypass) the blockage.

Last Updated August 2020